Other Cell-Based Assays

CXCR1 or C-X-C motif chemokine receptor 1, a key member of the GPCR family, plays an essential role in the immune response and is associated with inflammatory and immune disorders, including neutrophil recruitment in conditions such as asthma, chronic obstructive pulmonary disease (COPD), and cancer metastasis,...

CXCR4, or C-X-C motif chemokine receptor 4, is a key member of the GPCR family that plays a critical role in immune system regulation, cell migration, and tissue homeostasis and is implicated in various pathological processes, including HIV entry, cancer metastasis, and inflammatory diseases, making it a significant...

Chemokine (CC) receptor type 1 (CCR1), a key member of the GPCR family, is implicated in various inflammatory and immune-related disorders, making it an important therapeutic target. Traditional methods for studying GPCRs often fail to address the signaling mechanisms of specific GPCRs like CCR1, which couple to...

CCR5 or Chemokine (CC) receptor type 5 is a member of the GPCR family that plays a crucial role in immune responses and is involved in the pathogenesis of various diseases, including HIV infection, where it serves as a co-receptor for viral entry. Additionally, CCR5 has been associated with inflammatory diseases,...

Dopamine receptor D1 (D1R) is a key member of the G-protein coupled receptor (GPCR) family, involved in several physiological processes, including motor control, reward, learning, and memory. Dysregulation of D1R signaling is implicated in various neurological disorders, such as Parkinson's disease, schizophrenia,...

Cayman's Lipid Droplets Fluorescence Assay Kit can be used to study regulators of lipid droplet biogenesis. The main advantage of this assay is that the green fluorescence of Nile Red is both very sensitive and specific for lipid droplets. Furthermore, changes in lipid droplet biogenesis in various cell types in...

Cayman's E. coli Phagocytosis Assay Kit employs FITC-labeled, heat-inactivated E. coli cells for the measurement of the phagocytic process in vitro. The engulfed fluorescent E. coli can be detected by flow cytometry.Origin: Animal/Bovine.

Nucleosomes, which fold chromosomal DNA, contain two molecules each of the core histones H2A, H2B, H3, and H4. Almost two turns of DNA are wrapped around this octameric core, which represses transcription. The histone amino termini extend from the core, where they can be modified post-translationally by acetylation,...

Efferocytosis is a specialized form of phagocytosis in which macrophages and other phagocytic cells clear dead and dying cells to promote homeostasis, embryonic development, regulation of the immune system and the resolution of inflammation. Efficient clearance of cells is essential for the removal of the nearly 1...

Chloride channels have a variety of important physiological and cellular functions that include regulation of pH, volume homeostasis, organic solute transport, cell migration, cell proliferation and differentiation. Chloride channels represent valuable drug targets. A number of chronic disease states such as cystic...

The mechanism for the movement of cholesterol from intracellular sites to their ultimate cellular destination is an unresolved question of fundamental importance to cell biology and medicine. Thus, defining mechanisms of intracellular cholesterol transport and identifying the cellular factors involved are therefore...

This particular kit is designed to uniformly label live cells in green fluorescence for the studies that require the fluorescent tag molecules retained inside cells for relatively longer time.