Cell Meter(TM) Mitochondrial Membrane Potential Assay Kit *Orange Fluorescence Optimized for Flow Cy

Cell Meter(TM) Mitochondrial Membrane Potential Assay Kit *Orange Fluorescence Optimized for Flow Cy
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABD-22804 1 kit -

3 - 8 business days*

230.00€
 
This particular kit is designed to detect cell apoptosis by measuring the loss of the... more
Product information "Cell Meter(TM) Mitochondrial Membrane Potential Assay Kit *Orange Fluorescence Optimized for Flow Cy"
This particular kit is designed to detect cell apoptosis by measuring the loss of the mitochondrial membrane potential(MMP). The collapse of mitochondrial membrane potential coincides with the opening of the mitochondrial permeability transition pores, leading to the release of cytochrome C into the cytosol, which in turn triggers other downstream events in the apoptotic cascade. Our Cell Meter(TM) Orange Mitochondrial Membrane Potential Assay Kit provides all the essential components with an optimized assay method. This fluorimetric assay uses our proprietary cationic MitoLite(TM) Orange for the detection of apoptosis in cells with the loss of mitochondrial membrane potential. In normal cells, the red fluorescence intensity is increased when MitoLite(TM) Orange is accumulated in the mitochondria. However, in apoptotic cells, the fluorescence intensity of MitoLite(TM) Orange is decreased following the collapse of MMP. Cells stained with MitoLite(TM) Orange can be visualized with a flow cytometer at 488 nm excitation with red emission (FL2 channel). The kit can be used together with other reagents, such as Cell Meter(TM) Phosphatidylserine Apoptosis Assay Kit (ABD-22835) for multi-parametric study of cell vitality and apoptosis. The kit is optimized for screening apoptosis activators and inhibitors with a flow cytometer.
Supplier: AAT Bioquest
Supplier-Nr: 22804

Properties

Application: Apoptosis studies
Format: Homog.

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
Caution
Our products are for laboratory research use only: Not for administration to humans!
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