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Screen Quest(TM) Live Cell cAMP Assay Service Pack
Item number: ABD-36383
Excitation (nm): 490. Emission (nm): 525. Quantum yield: 0.95. G protein coupled receptors (GPCR) are one of the largest receptor classes targeted by drug discovery programs. Calcium flux (coupled via Gq pathway) assay is a preferred method in drug discovery for screening GPCR targets. However, over 60% of the known...
| Keywords: | FDSS, FLIPR, ViewLux, NOVOStar, ArrayScan, FlexStation, IN Cell Analyzer |
| Application: | Real-time intracellular cAMP change monitoring |
2,635.00€
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Screen Quest(TM) Live Cell cAMP Assay Service Pack
Item number: ABD-36384
Excitation (nm): 490. Emission (nm): 525. Quantum yield: 0.95. G protein coupled receptors (GPCR) are one of the largest receptor classes targeted by drug discovery programs. Calcium flux (coupled via Gq pathway) assay is a preferred method in drug discovery for screening GPCR targets. However, over 60% of the known...
| Keywords: | FDSS, FLIPR, ViewLux, NOVOStar, ArrayScan, FlexStation, IN Cell Analyzer |
| Application: | Real-time intracellular cAMP change monitoring |
6,687.00€
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Cell Meter(TM) Beta-Arrestin Translocation GPCR Signaling...
Item number: ABD-36390
Excitation: FITC filter set. Emission: FITC filter set. Virtually all G protein coupled receptors (GPCRs) rapidly undergo desensitization by a common pathway upon activation by ligand binding. The binding of beta-arrestin, a cytoplasmic protein, to an activated receptor deactivates the GPCR signaling and initiates...
| Application: | beta-arrestin translocation monitoring |
1,015.00€
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Cell Meter(TM) Beta-Arrestin Translocation GPCR Signaling...
Item number: ABD-36391
Excitation: FITC filter set. Emission: FITC filter set. Virtually all G protein coupled receptors (GPCRs) rapidly undergo desensitization by a common pathway upon activation by ligand binding. The binding of beta-arrestin, a cytoplasmic protein, to an activated receptor deactivates the GPCR signaling and initiates...
| Application: | beta-arrestin translocation monitoring |
1,286.00€
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Nuclear Factor of Activated T cells (NFAT)
Item number: IB-IB18001
This Nuclear Factor of Activated T cells (NFAT) kit product is an all-inclusive assay system that includes addition to NFAT Reporter Cells, two optimized media for use during cells culture and in diluting test samples, the calcineurin-NFAT pathway activator Ionomycin, Luciferase Detection Reagent, and a cell...
| Application: | Functional activity screening |
From 1,588.00€
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Nuclear Factor of Activated T cells (NFAT)
Item number: IB-IB18002
This Nuclear Factor of Activated T cells (NFAT) kit product is an all-inclusive assay system that includes addition to NFAT Reporter Cells, two optimized media for use during cells culture and in diluting test samples, the calcineurin-NFAT pathway activator Ionomycin, Luciferase Detection Reagent, and a cell...
| Application: | Functional activity screening |
4,175.00€
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Cannabinoid Type 1 Receptor (CB1R) Reporter Assay System...
Item number: IB-IB19002
This assay uses proprietary human cells that provide constitutive expression of the Human Cannabinoid Type 1 Receptor, also referred to as CB1R. CB1R is one of the two main cannabinoid receptors identified as part of the endocannabinoid system. CB1R is highly expressed in the central nervous system, but also in...
| Keywords: | CB1, CNR, CB-R, CNR1, CANN6, Cannabinoid receptor 1 |
| Application: | Functional activity screening |
| Species reactivity: | Human |
4,175.00€
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Fibroblast Growth Factor Receptors 1 & 2 for Paracrine...
Item number: IB-IB21002
The family of Fibroblast Growth Factors (FGFs) comprise approximately 23 members that are related by core sequence and structure conservation, with the majority of FGFs being secreted signaling proteins. Secreted FGFs are predominantly autocrine and paracrine factors, with only three members evolved to function as...
| Keywords: | CD331, FLT-2, FGFR1, BFGFR, N-sam, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fms-like tyrosine kinase 2, Fibroblast growth... |
| Application: | Functional activity screening |
| Species reactivity: | Human |
4,175.00€
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Bucculite(TM) XdU Cell Proliferation Fluorescence Imaging...
Item number: ABD-22327
Monitoring cell proliferation is one of the most reliable methods to assess cell viability, cell cycles and genotoxicity. An essential way to detect cell proliferation is to measure DNA synthesis in the presence of thymidine during the S-phase of cells growth. Bucculite(TM) XdU Cell Proliferation Fluorescence...
| Application: | FM, Cell viability / cell cycle / genotoxicity assays |
673.00€
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Human PDGFR a/b Reporter Assay System
Item number: IB-IB23001
This Human Platelet-Derived Growth Factor Receptors alpha and beta (PDGFRalpha/beta) reporter assay kit is an all-inclusive firefly luciferase reporter assay system that includes in addition to PDGFRalpha/beta Reporter Cells, an optimized culture medium for use in reviving the cryopreserved cells, a culture medium...
| Keywords: | UR, Lxrb, Nr1h2, Liver X receptor beta, Orphan nuclear receptor OR-1, Oxysterols receptor LXR-beta, Ubiquitously-expressed... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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Human PDGFR a/b Reporter Assay System
Item number: IB-IB23002
This Human Platelet-Derived Growth Factor Receptors alpha and beta (PDGFRalpha/beta) reporter assay kit is an all-inclusive firefly luciferase reporter assay system that includes in addition to PDGFRalpha/beta Reporter Cells, an optimized culture medium for use in reviving the cryopreserved cells, a culture medium...
| Keywords: | UR, Lxrb, Nr1h2, Liver X receptor beta, Orphan nuclear receptor OR-1, Oxysterols receptor LXR-beta, Ubiquitously-expressed... |
| Application: | Functional activity screening |
| Species reactivity: | human |
4,175.00€
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Mouse LXRb Reporter Assay System
Item number: IB-M00301
This Mouse Liver X Receptor Beta (mLXRbeta) assay kit is an all-inclusive firefly luciferase reporter assay system that includes in addition to mLXRbeta Reporter Cells, two optimized media for use during cell culture and (optionally) in diluting the test samples, a reference agonist, Luciferase Detection Reagent, a...
| Keywords: | Lxrb, Nr1h2, Liver X receptor beta, Oxysterols receptor LXR-beta, Ubiquitously-expressed nuclear receptor, Retinoid X... |
| Application: | Functional activity screening |
| Species reactivity: | mouse |
From 1,588.00€
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