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Neutrophil Elastase Activity Assay Kit
Item number: Cay600610-192
Cayman's Neutrophil Elastase Activity Assay kit employs a specific non-fluorescent elastase substrate, (Z-Ala-Ala-Ala-Ala)2Rh110, which is selectively cleaved by elastase to yield the highly fluorescent compound R110. Fluorescence can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
| Keywords: | HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone... |
| Application: | Neutrophile elastase detection |
| Species reactivity: | human |
686.00€
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Reporter Assay Panel for Calcitonin and Amylin Receptors
Item number: Cay502933-1
Cayman's reverse transfection reporter assays have overcome many of the disadvantages of other transfection approaches. In this method, a proprietary transfection complex containing DNA and an optimized mixture of lipids and proteins has been evenly applied and processed on the culture surface of multi-well plates....
| Keywords: | CTR/AMYR |
| Application: | Cell-based secreted alkaline phosphatase reporter assay panel |
| Species reactivity: | human |
832.00€
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Elk-1 Reporter Assay System (human)
Item number: IB-IB22111
Protein Function: Transcription factor that binds to purine-rich DNA sequences (PubMed:10799319, PubMed:7889942). Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2 (PubMed:1630903). Induces target gene...
| Keywords: | ELK1, ETS domain-containing protein Elk-1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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PDGFRbeta Inhibition Reporter Assay System (human)
Item number: IB-IB23201
Protein Function: Tyrosine-protein kinase that acts as a cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an...
| Keywords: | PDGFRB, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, Beta platelet-derived growth factor... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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GIPR Inhibition Reporter Assay System (human)
Item number: IB-IB38101
Protein Function: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase [The Uniprot Consortium]
| Keywords: | GIPR, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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MC1R Reporter Assay System (human)
Item number: IB-IB41101
Protein Function: Receptor for MSH (alpha, beta and gamma) and ACTH (PubMed:11442765, PubMed:11707265, PubMed:1325670, PubMed:1516719, PubMed:8463333). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11707265, PubMed:1325670, PubMed:16463023, PubMed:19737927)....
| Keywords: | MC1R, Melanocortin receptor 1, Melanocyte-stimulating hormone receptor |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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MC3R Reporter Assay System (human)
Item number: IB-IB41301
Protein Function: Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2 (By similarity). Induces target gene transcription upon JNK and...
| Keywords: | Elk1, ETS domain-containing protein Elk-1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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MC4R Reporter Assay System (human)
Item number: IB-IB41401
Protein Function: Hormone receptor that acts as a key component of the leptin-melanocortin pathway at the intersection of homeostatic maintenance of energetic state (PubMed:32327598, PubMed:33858992). Plays a role in regulating food intake: activation by a stimulating hormone such as anorexigenic alpha-melanocyte...
| Keywords: | MC4R, Melanocortin receptor 4 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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MC5R Reporter Assay System (human)
Item number: IB-IB41501
Protein Function: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins [The Uniprot Consortium]
| Keywords: | MC-2, MC5R, Melanocortin receptor 5 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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FGFR3c/beta-Klotho Reporter Assay System (human)
Item number: IB-IB42101
Protein Function: Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and...
| Keywords: | FGFR3, Fibroblast growth factor receptor 3 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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AMY3R Reporter Assay System (human)
Item number: IB-IB48001
Protein Function: Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1) (PubMed:23674134, PubMed:9620797). Required for the...
| Keywords: | RAMP3, Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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AMY1R Reporter Assay System (human)
Item number: IB-IB48101
Protein Function: Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed:33602864, PubMed:9620797, PubMed:35324283, PubMed:38603770). Required for the transport of...
| Keywords: | RAMP1, Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,588.00€
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