Cell-based Assays

In modern life science and pharmaceutical research cell-based assays are becoming increasingly important. Real-time measurements with cells offer the possibility of successful quantification of cell viability, cytotoxicity and biological activity. By realistically representing the situation in vivo, these assays enable direct analysis of cell responses and play an important role in understanding disease mechanisms.

In modern life science and pharmaceutical research cell-based assays are becoming increasingly important. Real-time measurements with cells offer the possibility of successful quantification of... read more »
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Cell-based Assays

In modern life science and pharmaceutical research cell-based assays are becoming increasingly important. Real-time measurements with cells offer the possibility of successful quantification of cell viability, cytotoxicity and biological activity. By realistically representing the situation in vivo, these assays enable direct analysis of cell responses and play an important role in understanding disease mechanisms.

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Glycolysis Cell-Based Assay Kit
Glycolysis Cell-Based Assay Kit

Item number: Cay600450-1

Cayman's Glycolysis Cell-Based Assay Kit provides a colorimetric method for detecting L-lactate, the end product of glycolysis, produced and secreted by cultured cells. In this assay, lactate dehydrogenase catalyzes the reaction between NAD+ and lactate, yielding pyruvate and NADH. The NADH directly reduces a...
Keywords: Glycolysis
Application: Extracellular L-lactate detection
529.00€ *
Review
Neutrophil Elastase Activity Assay Kit
Neutrophil Elastase Activity Assay Kit

Item number: Cay600610-192

Cayman's Neutrophil Elastase Activity Assay kit employs a specific non-fluorescent elastase substrate, (Z-Ala-Ala-Ala-Ala)2Rh110, which is selectively cleaved by elastase to yield the highly fluorescent compound R110. Fluorescence can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
Keywords: HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone...
Application: Neutrophile elastase detection
Species reactivity: human
686.00€ *
Review
Extracellular Oxygen Consumption Assay Kit
Extracellular Oxygen Consumption Assay Kit

Item number: Cay502880-1

Cayman's Extracellular Oxygen Consumption Assay Kit uses a phosphorescent oxygen-sensitive probe. Because of its inability to cross the membrane, the probe selectively reports on changes in oxygen levels in the medium. The probe's signal is quenched upon binding to oxygen, resulting in a signal that is inversely...
Keywords: OCR
Application: Phosphorescent assay, live cell/mitochondria oxygen consumption measurement
689.00€ *
Review
Cell Meter(TM) Phosphatidylserine Apoptosis Assay Kit *Green Fluorescence*
Cell Meter(TM) Phosphatidylserine Apoptosis Assay Kit...

Item number: ABD-22791

Designed to monitor cell apoptosis through measuring the translocation of phosphatidylserine (PS). The PS sensor used in this kit is a single fluorophore-labeled Annexin V that is specially modified to bind PS more tightly.
Keywords: Apopxin PS
Application: Apoptosis assay
291.00€ *
Review
Autophagy/Cytotoxicity Dual Staining Kit
Autophagy/Cytotoxicity Dual Staining Kit

Item number: Cay600140-1

Autophagy is a critical cellular process that involves the degradation and digestion of intracellular components by the lysosome. This process not only enables cells to efficiently mobilize and recycle cellular constituents, but also prevents the accumulation of damaged organelles, misfolded proteins, and invading...
Application: Fluorescence
452.00€ *
Review
Cell Meter(TM) Fluorimetric Phagocytosis Assay Kit   *Enhanced Red Fluorescence*
Cell Meter(TM) Fluorimetric Phagocytosis Assay Kit...

Item number: ABD-21234

The Cell Meter(TM) Fluorimetric Phagocytosis Assay Kit (Enhanced Red Fluorescence) is designed to evaluate phagocytic activity in live cells. Phagocytosis is a cellular process in which cells engulf and digest particles, such as pathogens or cellular debris, to maintain homeostasis. It features a ready-to-use...
Application: Robust, sensitive phagocytic activity detection in live cells
560.00€ *
Review
Cell Meter(TM) Direct Cell Proliferation Assay Kit
Cell Meter(TM) Direct Cell Proliferation Assay Kit

Item number: ABD-22506

Cell Meter(TM) Direct Cell Proliferation Assay Kit offers an easy solution for quantifying cell proliferation and cytotoxicity in live cell populations. The assay is based on a proprietary cell-permeant DNA-binding dye paired with a signal enhancer that prevents dead-cell staining, ensuring that only intact, live...
Application: Cell proliferation/cytotoxicity assessment, HTS
261.00€ *
Review
Screen Quest(TM) Live Cell Opioid-Like receptor hMOR1 cAMP Assay Service Pack
Screen Quest(TM) Live Cell Opioid-Like receptor hMOR1...

Item number: ABD-38209

hMOR1, also known as the Human Mu Opioid Receptor (MOR1), is a key member of the G-protein coupled receptor (GPCR) family. hMOR1 is a critical target for opioid-based analgesics and is implicated in various disorders, including chronic pain, opioid addiction, and other neurological conditions. Traditional methods...
Application: Real-time cAMP monitoring, HTS
2,433.00€ *
Review
Screen Quest(TM) Live Cell Opioid-Like receptor hKOR cAMP Assay Service Pack
Screen Quest(TM) Live Cell Opioid-Like receptor hKOR cAMP...

Item number: ABD-38211

hKOR, also known as the Human Kappa Opioid Receptor, is a key member of the G-protein coupled receptor (GPCR) family, involved in various neurological and psychiatric conditions, including pain management, depression, and addiction. Traditional methods for studying GPCRs often fail to address the full spectrum of...
Application: Real-time cAMP monitoring, HTS
2,433.00€ *
Review
Screen Quest(TM) Live Cell Somatostatin receptor 1 (SSTR1) cAMP Assay Service Pack
Screen Quest(TM) Live Cell Somatostatin receptor 1...

Item number: ABD-38214

Somatostatin receptor 1 (SSTR1), a key GPCR, plays an essential role in regulating endocrine and nervous system functions by inhibiting adenylyl cyclase activity and decreasing intracellular cAMP levels. Dysregulated SSTR1 signaling is associated with various conditions, including neuroendocrine tumors, pituitary...
Application: Real-time cAMP monitoring, HTS
2,433.00€ *
Review
XTT Assay
XTT Assay

Item number: ABD-22774

The XTT assay is a fast and reliable method for measuring cell viability and proliferation. Based on the reduction of the XTT tetrazolium compound by metabolically active cells, this kit produces a soluble formazan product that can be quantified through absorbance at 450 nm. The assay eliminates the need for washing...
Application: Cytotoxicity screening, HTS
From 416.00€ *
Review
Screen Quest(TM) Live Cell Chemokine (CC) receptor CCR3 cAMP Assay Service Pack
Screen Quest(TM) Live Cell Chemokine (CC) receptor CCR3...

Item number: ABD-38202

CCR3 or Chemokine (CC) receptor type 3, a key member of the GPCR family, is critically involved in various inflammatory and allergic conditions, including asthma, eosinophilic disorders, and certain autoimmune diseases, making it an important therapeutic target. Traditional methods for studying GPCRs often fail to...
Application: Real-time cAMP monitoring, HTS
2,433.00€ *
Review
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