Cell-based Assays

In modern life science and pharmaceutical research cell-based assays are becoming increasingly important. Real-time measurements with cells offer the possibility of successful quantification of cell viability, cytotoxicity and biological activity. By realistically representing the situation in vivo, these assays enable direct analysis of cell responses and play an important role in understanding disease mechanisms.

In modern life science and pharmaceutical research cell-based assays are becoming increasingly important. Real-time measurements with cells offer the possibility of successful quantification of... read more »
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Cell-based Assays

In modern life science and pharmaceutical research cell-based assays are becoming increasingly important. Real-time measurements with cells offer the possibility of successful quantification of cell viability, cytotoxicity and biological activity. By realistically representing the situation in vivo, these assays enable direct analysis of cell responses and play an important role in understanding disease mechanisms.

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Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit (Red Fluorescence)
Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit...

Item number: ABD-22797

Our Cell Meter(TM) assay kits are a set of tools for monitoring cell viability. There are a variety of parameters that can be used for monitoring cell viability. This particular kit is designed to monitor cell apoptosis through measuring Caspase 3 activation. Caspase 3 is widely accepted as a reliable indicator for...
Keywords: CASP3, CPP32, SCA-1, CPP-32, CASP-3, Apopain, Caspase-3, EC=3.4.22.56, MCH3, CASP7, CMH-1, CASP-7, ICE-LAP3, Caspase-7,...
Application: Caspase-3 assays
434.00€ *
Review
AR (human) Reporter Assay Kit
AR (human) Reporter Assay Kit

Item number: IB-IB03001

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Keywords: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Application: Functional activity screening
Species reactivity: human
From 1,588.00€ *
Review
Cell Meter(TM) TUNEL Apoptosis Assay Kit
Cell Meter(TM) TUNEL Apoptosis Assay Kit

Item number: ABD-22844

DNA fragmentation represents a characteristic of late stage apoptosis. DNA fragmentation in apoptotic cells can be detected by terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL). The TUNEL assay relies on the presence of nicks in the DNA which can be identified by TdT, an enzyme that...
Application: TUNEL apoptosis assay
434.00€ *
Review
RORgamma (human) Reporter Assay Kit
RORgamma (human) Reporter Assay Kit

Item number: IB-IB04001

This human RAR-related orphan receptor gamma (RORgamma) mRNA is expressed from the RORC gene in two forms via alternate usage of tissue-specific promoters. Variant 1 mRNA is expressed in numerous tissues, and encodes receptor isoform 1, referred to as RORgamma. Variant 2 mRNA comprises an alternate exon 1 that...
Keywords: RORC, NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan receptor C, Retinoid-related...
Application: Functional activity screening
Species reactivity: human
From 1,588.00€ *
Review
Human GHR Reporter Assay System
Human GHR Reporter Assay System

Item number: IB-IB14001

The principle application of this assay product is in the screening of test samples to quantify functional activities, either agonist or antagonist. This kit product is an all-inclusive assay system that includes, in addition to Reporter Cells, two optimized media for use during cell culture and (optionally) in...
Keywords: GHR
Application: Functional activity screening
Species reactivity: Human
From 1,588.00€ *
Review
NEW
Reporter Assay Panel for Calcitonin and Amylin Receptors
Reporter Assay Panel for Calcitonin and Amylin Receptors

Item number: Cay502933-1

Cayman's reverse transfection reporter assays have overcome many of the disadvantages of other transfection approaches. In this method, a proprietary transfection complex containing DNA and an optimized mixture of lipids and proteins has been evenly applied and processed on the culture surface of multi-well plates....
Keywords: CTR/AMYR, CALCR, RAMP1, RAMP2, RAMP3
Application: Cell-based secreted alkaline phosphatase reporter assay panel
Species reactivity: human
832.00€ *
Review
FLICA(TM) 660 Caspase 3/7 Assay Kit, far-red fluorescence  (25-50 tests)
FLICA(TM) 660 Caspase 3/7 Assay Kit, far-red fluorescence...

Item number: ICT-9125

The far-red FLICA® 660-DEVD-FMK caspase-3 detection probe is comprised of the preferred affinity peptide sequence (DEVD) targeted by activated caspase-3 and caspase-7, a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK) reactive moiety. The resulting fluorescent caspase-3 inhibitor probe forms an...
Keywords: Apoptosis kit, CASP3, CPP32, SCA-1, CPP-32, CASP-3, Apopain, Caspase-3, EC=3.4.22.56, Protein Yama, Cysteine protease...
Application: FM, FC, Apoptosis detection
387.00€ *
Review
FAM-FLICA(R) Caspases 3 & 7 Assay Kit
FAM-FLICA(R) Caspases 3 & 7 Assay Kit

Item number: ICT-93

This kits makes use of a cell-permeant green fluorecent probe (FAM-DEVD-FMK ) that binds to active caspase-3 & 7 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
Keywords: Apoptosis kit
Application: FM, FC, Apoptosis detection
327.00€ *
Review
Cell Meter(TM) JC-10 Mitochondrial Membrane Potential Assay Kit *Optimized for Flow Cytometry Assays
Cell Meter(TM) JC-10 Mitochondrial Membrane Potential...

Item number: ABD-22801

Although JC-1 is widely used in many labs, its poor water solubility causes extraordinary inconvenience. Even at 1 µM concentration, JC-1 tends to precipitate in aqueous buffer. JC-10 is developed to be a superior alternative to JC-1 where high dye concentration is desired. Compared to JC-1, JC-10 has much better...
Application: FC, Apoptosis studies
434.00€ *
Review
WST-8 Cell Proliferation Assay Kit
WST-8 Cell Proliferation Assay Kit

Item number: Cay10010199-480

Cayman's WST-8 Cell Proliferation Assay provides a tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of WST-8 by NADH produced in the mitochondria resulting in a water-soluble formazan which dissolves directly into the culture...
Application: Cell based assays
From 153.00€ *
Review
LDH Cytotoxicity Assay Kit
LDH Cytotoxicity Assay Kit

Item number: Cay601170-96

Necrosis is accompanied by mitochondrial swelling and increased plasma membrane permeability, while apoptosis involves an articulated breakdown of the cell into membrane-bound apoptotic bodies. Lactate dehydrogenase (LDH) is a soluble cytosolic enzyme that is released into the culture medium following loss of...
Keywords: Lactate Dehydrogenase Cytotoxicity Assay Kit
Application: Cell based assays
Species reactivity: broad
From 305.00€ *
Review
Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit * Blue Fluorescence*
Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit *...

Item number: ABD-22795

This kit uses Ac-DEVD-AMC as a fluorogenic indicator for caspase-3 activity. Sufficient reagents to perform 500 assays. Using 25µl of reagents per well in a 384-well format, this kit provides sufficient reagents to perform 2,000 assays.
Application: Apoptosis assay
291.00€ *
Review
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