PAD2 Inhibitor Screening Assay Kit (Ammonia)

PAD2 Inhibitor Screening Assay Kit (Ammonia)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay701400-96 96 wells -

6 - 10 business days*

661.00€
 
Protein Arginine Deiminase 2 (PAD2) is a guanidino-modifying enzyme that catalyzes the conversion... more
Product information "PAD2 Inhibitor Screening Assay Kit (Ammonia)"
Protein Arginine Deiminase 2 (PAD2) is a guanidino-modifying enzyme that catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. This enzyme has been implicated in several diseases, including rheumatoid arthritis (RA), retinal degeneration, and certain cancers. PAD2 has been shown to modify vimentin, fibrinogen and beta/gamma-actin. Extracellular levels of PAD2 are increased in the lungs of smokers, providing a link between smoking as a risk factor for RA and anti-citrullinated protein antibodies among RA patients. Cayman's PAD2 Inhibitor Screening Assay (Ammonia) provides a convenient method for screening human PAD2 inhibitors.Synonyms: PADI2, PAD-H19, Peptidylarginine Deiminase 2, Protein Arginine Deiminase 2.
Keywords: PAD-H19, PADI2, Peptidylarginine Deiminase 2, Protein Arginine Deiminase 2
Supplier: Cayman Chemical
Supplier-Nr: 701400

Properties

Application: Fluorescence, HTS
Species reactivity: human
Format: Homog.

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H301, H302, H314, H315, H317, H319, H336, H361, H370, H372, H410
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P273, P280, P312, P314, P321, P363, P391, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P311, P308+P313, P332+P313, P333+P313, P337+P313, P362+P364, P370+P378
Caution
Our products are for laboratory research use only: Not for administration to humans!
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