PAD2 Inhibitor Screening Assay Kit (AMC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
Cay701390-96	96 wells		-		6 - 10 business days*		661.00€

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Protein arginine deiminase 2 (PAD2) is a guanidino-modifying enzyme that catalyzes the conversion... more

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Product information "PAD2 Inhibitor Screening Assay Kit (AMC)"

Protein arginine deiminase 2 (PAD2) is a guanidino-modifying enzyme that catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. This enzyme has been implicated in several diseases, including rheumatoid arthritis (RA), retinal degeneration, and certain cancers. PAD2 has been shown to modify vimentin, fibrinogen, and beta/gamma-actin. Extracellular levels of PAD2 are increased in the lungs of smokers, providing a link between smoking as a risk factor for RA and anti-citrullinated protein antibodies among RA patients. Cayman's PAD2 Inhibitor Screening Assay Kit (AMC) provides a convenient method for screening human PAD2 inhibitors.Synonyms: PADI2, PAD-H19, Peptidylarginine Deiminase 2, Protein Arginine Deiminase 2.

Keywords:	PAD-H19, PADI2, Peptidylarginine Deiminase 2, Protein Arginine Deiminase 2
Supplier:	Cayman Chemical
Supplier-Nr:	701390

Properties

Application:	HTS
Format:	Homog.

Database Information

KEGG ID :	K01481 \| Matching products
UniProt ID :	Q9Y2J8 \| Matching products
Gene ID	GeneID 11240 \| Matching products

Handling & Safety

Storage:	-80°C
Shipping:	-80°C (International: -80°C)
Signal Word:	Danger
GHS Hazard Pictograms:
H Phrases:	H302, H315, H316, H319, H334, H402
P Phrases:	P261, P264, P270, P273, P280, P284, P301+310, P302+352, P304+341, P305+351+338, P321, P330, P332+313, P337+313, P342+311, P362+364, P501