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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
V2110-19D.10 | 10 blots | - | - |
3 - 19 business days* |
909.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Vascular Endothelial Growth Factor Receptor 2 (VEGFR2, also known as KDR/FLK-1) is a ~200kD... more
Product information "Anti-phospho-Vascular Endothelial Growth Factor Receptor 2 (Tyr1054, Tyr1059) (VEGF R2, Flk1, KDR, R"
Vascular Endothelial Growth Factor Receptor 2 (VEGFR2, also known as KDR/FLK-1) is a ~200kD member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors upon ligand binding, VEGFR2 forms a dimer and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2- and phosphotyrosine binding domain containing signaling proteins. Phosphorylation of tyrosines 1054 and 1059 in the activation loop is required for activation of VEGFR2 and its intrinsic tyrosine kinase activity. Applications: Suitable for use in Western blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, Optimal dilution to be determined by researcher. Positive Controls: Porcine aortic endothelial (PAE) cells transfected with a chimeric receptor consisting of the extracellular portion of the CSF-1 receptor fused with the transmembrane and intracellular domains of mouse VEGFR2. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | EC=2.7.10.1, Anti-phospho-FLK-1, Anti-phospho-CD309, Anti-phospho-VEGFR-2, Anti-phospho-Fetal liver kinase 1, Anti-phospho-Kinase insert domain receptor, Anti-phospho-Protein-tyrosine kinase receptor flk-1 |
Supplier: | United States Biological |
Supplier-Nr: | V2110-19D |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthetic phosphopeptide corresponding to a region of human Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) that contains Tyr1054 and Tyr1059. Species Sequence Homology: Mouse, rat |
Format: | Affinity Purified |
Database Information
KEGG ID : | K05098 | Matching products |
UniProt ID : | P35968 | Matching products |
Gene ID | GeneID 3791 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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