Anti-phospho-TSC2 (Thr1462)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F53757-0.08ML	80 µl		-	-	3 - 10 business days*		361.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. Mutations in TSC2 lead to tuberous sclerosis complex.... more

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Product information "Anti-phospho-TSC2 (Thr1462)"

In 1X PBS, pH 7.4, with 0.09% sodium azide. Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

Keywords:	Anti-phospho-TSC2, Anti-phospho-Tuberin, Anti-phospho-Tuberous sclerosis 2 protein, Phospho-TSC2 Antibody (pT1462)
Supplier:	NSJ Bioreagents
Supplier-Nr:	F53757

Properties

Application:	DB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	This phospho-TSC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT1462 of human TSC2.
Format:	Purified