Anti-phospho-TERT (Tyr707) (Telomerase Reverse Transcriptase, Telomerase Catalytic Subunit, HEST2, T

Anti-phospho-TERT (Tyr707) (Telomerase Reverse Transcriptase, Telomerase Catalytic Subunit, HEST2, T
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T2399-25E.200 200 µl - -

1 - 19 business days

557.00€
 
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the... more
Product information "Anti-phospho-TERT (Tyr707) (Telomerase Reverse Transcriptase, Telomerase Catalytic Subunit, HEST2, T"
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: EC=2.7.7.49, Anti-phospho-Telomerase catalytic subunit, Anti-phospho-Telomerase-associated protein 2, Anti-phospho-Telomerase reverse transcriptase
Supplier: United States Biological
Supplier-Nr: T2399-25E

Properties

Application: ELISA, Dot Blot
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Y707 of human TERT (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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