96 products were found matching "K11126"!
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360A (iodide)
Item number: Cay42501-10
360A is an inhibitor of telomerase (IC50 = 0. µM). It decreases the viability of in T98G glioma fibroblasts, CB193 astrocytoma and U-118 MG glioma cells, and primary human astrocytes (IC50s = 4. 3. 8. and 17. µM, respectively). 360A (5 µM) induces sister chromatid fusions and telomere loss in HeLa cervical cancer...
| Keywords: | 3,3'-[2,6-pyridinediylbis(carbonylimino)]bis[1-methyl-quinolinium, diiodide |
| Application: | Telomerase inhibitor |
| CAS | 737763-37-0 |
| MW: | 703.3 D |
From 259.00€
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Anti-Telomerase (hTERT Catalytic Unit)
Item number: 600-401-252
Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Keywords: | Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, EC=2.7.7.49, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated... |
| Application: | ELISA, IHC, IFM, IP, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 180.00€
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MST-312
Item number: TGM-T41290-10mg
Description: MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM). Target: Telomerase. Smiles: Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O. References: Ameri Z, et al....
| Keywords: | Telomerase Inhibitor IX |
| Application: | Telomerase inhibitor |
| CAS | 368449-04-1 |
| MW: | 380.35 D |
From 31.00€
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RHPS4
Item number: TGM-T6967-100mg
Description: RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar. Target: Apoptosis, Telomerase. Smiles: COS([O-])(=O)=O.Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23. References: Phatak P, et al. Br J Cancer. 2007, 96(8):1223-33.
| Keywords: | RHPS 4 methosulfate, NSC714187 |
| Application: | Telomerase inhibitor |
| CAS | 390362-78-4 |
| MW: | 458.48 D |
From 40.00€
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TERT Protein, Human, Recombinant (His)
Item number: TGM-TMPH-02186-100ug
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Keywords: | HEST2, Telomerase-associated protein 2, Telomerase catalytic subunit, TERT, Telomerase reverse transcriptase |
| MW: | 22.7 kD |
From 236.00€
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TRET Protein, Mouse, Recombinant (His & SUMO)
Item number: TGM-TMPH-02926-100ug
Description: TRET Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is O70372.
| Keywords: | Tert, Telomerase reverse transcriptase, Telomerase catalytic subunit |
| MW: | 54.1 kD |
From 359.00€
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6-Thio-2'-Deoxyguanosine
Item number: TGM-T6746-100mg
Description: 6-Thio-2'-Deoxyguanosine (beta-TGdR) is a nucleoside analog and telomerase substrate. Target: DNA/RNA Synthesis, Others. Smiles: Nc1nc(=S)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1. References: Mender I, et al. Cancer Discov. 2015, 5(1), 82-95.
| Keywords: | beta-TGdR, 6-Thio-dG |
| Application: | Nucleoside analog, telomeric DNA damage inducer |
| CAS | 789-61-7 |
| MW: | 283.31 D |
From 49.00€
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TMPyP4 tosylate
Item number: TGM-T13174-100mg
Description: TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and telomerase inhibitor that exhibits antitumor effects in osteosarcoma cell lines. Target: DNA/RNA Synthesis, Telomerase. Smiles:...
| Keywords: | TMP 1363 |
| Application: | G-quadruplex stabilizer, telomerase inhibitor |
| CAS | 36951-72-1 |
| MW: | 1363.6 D |
From 33.00€
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Cyclogalegenin
Item number: TGM-T3333-100mg
Description: Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals. Target: Telomerase. Smiles: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O)C3)(C(C)(C)[C@@H](O)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@@]6(C)O[C@@H]([C@@](C)(C)O)CC6)[H])[H]. References: de Jesus...
| Keywords: | Cyclogalegigenin, Astramembrangenin, Cyclogalagenin, Cycloastragenol |
| Application: | Reported telomerase activator |
| CAS | 84605-18-5 |
| MW: | 490.71 D |
From 30.00€
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Costunolide
Item number: TGM-T2902-100mg
Description: Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. Target: Endogenous Metabolite, Apoptosis, Telomerase. Smiles: [H][C@]12OC(=O)C(=C)[C@]1([H])CC\C(C)=C\CC\C(C)=C\2. References: Choi SH, et al, Cancer Lett, 2005, 227(2), 153-162.
| Keywords: | Costunolid, (+)-Costunolide, Costus lactone, NSC 106404 |
| Application: | Apoptosis inducer |
| CAS | 553-21-9 |
| MW: | 232.32 D |
From 49.00€
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beta-Rubromycin
Item number: TGM-T35428-1mg
Description: beta-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 µM, respectively. beta-rubromycin inhibits HIV-1 reverse transcriptase activity by...
| Application: | Human telomerase inhibitor, HIV-1 reverse transcriptase inhibitor |
| CAS | 27267-70-5 |
| MW: | 536.445 D |
From 214.00€
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Anti-TERT
Item number: CSB-PA004257.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated protein 2,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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