Anti-phospho-KCC2 / Potassium Chloride Cotransporter (Ser940)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG52400.50	50 µl		-	-	6 - 14 business days*		625.00€

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Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is... more

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Product information "Anti-phospho-KCC2 / Potassium Chloride Cotransporter (Ser940)"

Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (PubMed:9930699). Involved in the regulation of dendritic spine formation and maturation (PubMed:22345354). [The UniProt Consortium]

Keywords:	Anti-phospho-Kcc2, Anti-phospho-rKCC2, Anti-phospho-Slc12a5, Anti-phospho-K-Cl cotransporter 2, Anti-phospho-Neuronal K-Cl cotransporter, Anti-phospho-Solute carrier family 12 member 5, Anti-phospho-Furosemide-sensitive K-Cl cotransporter
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG52400

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	rat (Expected: human, mouse, bovine, dog, primates)
Immunogen:	Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser940 conjugated to KLH
MW:	126 kD
Format:	Affinity Purified

Database Information

KEGG ID :	K23967 \| Matching products
UniProt ID :	Q63633 \| Matching products
Gene ID :	GeneID 171373 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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