Anti-KCC2, clone S1-12

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG22238.50	50 µg		-	-	6 - 14 business days*		520.00€

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Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is... more

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Product information "Anti-KCC2, clone S1-12"

Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (PubMed:9930699). Involved in the regulation of dendritic spine formation and maturation (PubMed:22345354). [The UniProt Consortium]

Keywords:	Anti-Kcc2, Anti-rKCC2, Anti-Slc12a5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier family 12 member 5, Anti-Furosemide-sensitive K-Cl cotransporter, Anti-Electroneutral potassium-chloride cotransporter 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG22238

Properties

Application:	WB, IHC, IP
Antibody Type:	Monoclonal
Clone:	S1-12
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse, rat
Immunogen:	Fusion protein around aa. 932-1043 of Rat KCC2
MW:	140 kD
Format:	Purified