Anti-phospho-Dynamin (Ser774)

Anti-Dynamin pS774 antibody is directed against Dynamin. Anti-Dynamin pS774 antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated Dynamin pS774. Minimal reactivity occurs against non-phosphorylated Dynamin pS774. Reactivity is completely blocked by treatment with ?-phosphatase. Reactivity against Dynamin pS774 occurs from rat sources. However, reactivity is also expected against bovine, canine, chicken, human, mouse and NHP. Protein function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis. [The UniProt Consortium]