106 products were found matching "K01528"!

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.

Bis-T-23 is a promoter of dynamin oligomerization. It was originally discovered to inhibit phosphatidylserine-induced dynamin 1 GTPase activity (IC50 = 1.7 µM) but promotes dynamin oligomerization in COS-7 cells in an actin-dependent manner when used at a concentration of 30 µM and increases dynamin 1 GTPase...

Dynasore is a cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC50 = 15 µM). Through this action, dynasore inhibits clathrin-dependent vesicle formation and endocytosis, which is necessary for internalization of certain parasites and viruses, as well as...

Dynamin GTPase inhibitor, Endocytosis inhibitor, Viral infection inhibitor, Destabilizes actin filaments, Inhibits entry of Trypanosoma into macrophages.

Mdivi 1 is a mitochondrial division inhibitor. It inhibits the GTPase activity of yeast, but not human, dynamin-1 (Dnm1, IC50 = ~1-10 µM for the recombinant yeast enzyme) and human dynamin-related protein 1 (DRP1) in A549 lung cancer cells when used at a concentration of 50 µM. Mdivi 1 (50 µM) inhibits mitochondrial...

Dynamin inhibitor.

Anti-Dynamin pS774 antibody is directed against Dynamin. Anti-Dynamin pS774 antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any...

Anti-Dynamin pS778 antibody is directed against human Dynamin. Anti-Dynamin pS778 antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any...

Quinazolinone, mitochondrial division inhibitor.

Dynole 34-2 is an inhibitor of dynamin (IC50s = 6.9 and 14.2 µM for dynamin 1 and dynamin 2 GTPase activity, respectively). It induces multinucleation, inhibits cytokinesis, and induces apoptosis in HeLa cells when used at a concentration of 10 µM. Dynole 34-2 inhibits the proliferation of several cancer cell lines...

Description: Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 µM, 1.1 µM, and 2.3 µM, respectively. Target: Dynamin. Smiles: Oc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O. References: McCluskey A, et al. Traffic. 2013, 14(12), 1272-1289.

Protein function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis. [The UniProt Consortium]