Anti-phospho-Bcl-2 (Thr56)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG51567.50	50 µl		-	-	6 - 14 business days*		436.00€
ARG51567.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent... more

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Product information "Anti-phospho-Bcl-2 (Thr56)"

Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785). [The UniProt Consortium]

Keywords:	Anti-phospho-BCL2, Anti-phospho-Apoptosis regulator Bcl-2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG51567

Properties

Application:	IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Peptide sequence around phosphorylation site of threonine 56(G-H-T(p)-P-H) derived from Human Bcl-2
Format:	Affinity Purified