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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG59158.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase... more
Product information "Anti-WRN"
Protein function: Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double- stranded DNA. Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions. May play an important role in the dissociation of joint DNA molecules that can arise as products of homologous recombination, at stalled replication forks or during DNA repair. Alleviates stalling of DNA polymerases at the site of DNA lesions. Important for genomic integrity. Plays a role in the formation of DNA replication focal centers, stably associates with foci elements generating binding sites for RP-A. Plays a role in double-strand break repair after gamma-irradiation. [The UniProt Consortium]
Keywords: | Anti-WRN, Anti-RECQ3, Anti-RecQ3, EC=3.1.-.-, Anti-Exonuclease WRN, Anti-RecQ protein-like 2, Anti-DNA helicase, RecQ-like type 3, Anti-Werner syndrome ATP-dependent helicase |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG59158 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant fusion protein corresponding to aa. 1223-1432 of Human WRN (NP_000544.2) |
MW: | 162 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10900 | Matching products |
UniProt ID : | Q14191 | Matching products |
Gene ID | GeneID 7486 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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