Anti-WDR1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-471A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A305-471A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

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Protein function: Induces disassembly of actin filaments in conjunction with ADF/cofilin family... more

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Product information "Anti-WDR1"

Protein function: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:15629458). Enhances cofilin-mediated actin severing. Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance. Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP, the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension. Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed:25792565). [The UniProt Consortium]

Keywords:	Anti-AIP1, Anti-WDR1, Anti-NORI-1, Anti-Actin-interacting protein 1, Anti-WD repeat-containing protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-471A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine)
Immunogen:	synthetic peptide. The epitope recognized by A305-471A-T maps to a region between residue 125 to 175 of human WD repeat-containing protein 1 using the numbering given in entry O75083.4 (GeneID 9948).
Format:	Antigen Affinity Purified