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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00580-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00580 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
PARP4 [poly(ADP-ribose) polymerase family, member 4] catalyzes the formation of ADP-ribose... more
Product information "Anti-vPARP (IHC)"
PARP4 [poly(ADP-ribose) polymerase family, member 4] catalyzes the formation of ADP-ribose polymers covalently attached to proteins using NAD as a substrate. There are 6 mammalian PARP enzymes: PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrase-1, and PARP6/Tankyrase-2. PARP4 is also known as vault PARP (vPARP) due to its association with the vault particle, a 13MDa cytoplasmic ribonucleoprotein complex whose barrel-shaped structure resembles arched cathedral ceilings. vPARP has also been identified separate from the vault particle. It has been localized to the nuclear pore, mitotic spindle, and cytoplasm. It also has been shown to associate with telomerase activity. Studies of vPARP knockout mice show an increased susceptibility to carcinogen-induced tumorigenesis. vPARP is also known as PARP-related IalphaI-related H5/proline-rich, PH5P, p193, PARPL, VWA5C, VAULT3, ADPRTL1, and KIAA0777.
Keywords: | Anti-PH5P, Anti-ARTD4, Anti-VPARP, Anti-PARP4, Anti-PARP-4, Anti-ADPRTL1, EC=2.4.2.30, Anti-193 kDa vault protein, Anti-Poly [ADP-ribose] polymerase 4, Anti-Vault poly(ADP-ribose) polymerase, Anti-PARP-related/IalphaI-related H5/proline-rich |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00580 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: orangutan, rhesus monkey, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00580 maps to a region between residue 1674 to 1724 of human vault poly(ADP-ribose) polymerase using the numbering given in entry NP_006428.2 (GeneID 143). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K10798 | Matching products |
UniProt ID : | Q9UKK3 | Matching products |
Gene ID | GeneID 143 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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