Anti-VEGF, clone 4B2-8

Anti-VEGF, clone 4B2-8
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG56584.100 100 µg - -

6 - 14 business days*

518.00€
ARG56584.200 200 µg - -

6 - 14 business days*

752.00€
 
Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell... more
Product information "Anti-VEGF, clone 4B2-8"
Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. [The UniProt Consortium]
Keywords: Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG56584

Properties

Application: ELISA, WB, Neutr.
Antibody Type: Monoclonal
Clone: 4B2-8
Conjugate: No
Host: Mouse
Species reactivity: human (Expected: rat)
Immunogen: E. coli derived Recombinant Human VEGF.(APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR)
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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