Anti-VEGF (Biotin)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56586.50	50 µg		-	-	6 - 14 business days*		732.00€

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Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell... more

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Product information "Anti-VEGF (Biotin)"

Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. [The UniProt Consortium]

Keywords:	Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56586

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	Biotin
Host:	Rabbit
Species reactivity:	human (Expected: hamster, mouse)
Immunogen:	E. coli derived Recombinant Human VEGF.(APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR)
Format:	Affinity Purified