Anti-USP19/ZMYND9

Anti-USP19/ZMYND9
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-587A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A301-587A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A301-587A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Deubiquitinating enzyme that regulates the degradation of various proteins.... more
Product information "Anti-USP19/ZMYND9"
Protein function: Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains. [The UniProt Consortium]
Keywords: Anti-USP19, Anti-KIAA0891, EC=3.4.19.12, Anti-Ubiquitin thioesterase 19, Anti-Deubiquitinating enzyme 19, Anti-Ubiquitin carboxyl-terminal hydrolase 19, Anti-Ubiquitin-specific-processing protease 19, Anti-Zinc finger MYND domain-containing protein 9
Supplier: Bethyl Laboratories
Supplier-Nr: A301-587A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Dog, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, European Domestic Ferret, African Elephant)
Immunogen: synthetic peptide. The epitope recognized by A301-587A-T maps to a region between residue 900 and 950 of human ubiquitin specific peptidase 19 (zinc finger MYND domain-containing protein 9) using the numbering given in entry NP_006668.1 (GeneID 10869).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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