Anti-USP19/ZMYND9

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-586A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A301-586A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Deubiquitinating enzyme that regulates the degradation of various proteins.... more

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Product information "Anti-USP19/ZMYND9"

Protein function: Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains. [The UniProt Consortium]

Keywords:	Anti-USP19, Anti-KIAA0891, EC=3.4.19.12, Anti-Ubiquitin thioesterase 19, Anti-Deubiquitinating enzyme 19, Anti-Ubiquitin carboxyl-terminal hydrolase 19, Anti-Ubiquitin-specific-processing protease 19, Anti-Zinc finger MYND domain-containing protein 9
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-586A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: gorilla, chimpanzee)
Immunogen:	synthetic peptide. The epitope recognized by A301-586A-T maps to a region between residue 1 and 50 of human ubiquitin specific peptidase 19 (zinc finger MYND domain-containing protein 9) using the numbering given in entry NP_006668.1 (GeneID 10869).
Format:	Antigen Affinity Purified