Anti-USP16 / UBP-M, N-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG63336.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific... more

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Product information "Anti-USP16 / UBP-M, N-terminal"

Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T- lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. [The UniProt Consortium]

Keywords:	Anti-MSTP039, Anti-Ubiquitin thioesterase 16, Anti-Deubiquitinating enzyme 16, Anti-Ubiquitin-processing protease UBP-M, Anti-Ubiquitin carboxyl-terminal hydrolase 16, Anti-Ubiquitin-specific-processing protease 16
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG63336

Properties

Application:	ELISA, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human, bovine, dog
Immunogen:	GKKRTKGKTVPIDD-C
Format:	Ammonium Sulfate Precipitated