Anti-USP16

Anti-USP16
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-615A-T 10 µl (10 µg) -

3 - 9 business days

125.00€
A301-615A 100 µl (100 µg) -

3 - 9 business days

443.00€
 
Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific... more
Product information "Anti-USP16"
Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T- lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. [The UniProt Consortium]
Keywords: Anti-MSTP039, Anti-Ubiquitin thioesterase 16, Anti-Deubiquitinating enzyme 16, Anti-Ubiquitin-processing protease UBP-M, Anti-Ubiquitin carboxyl-terminal hydrolase 16, Anti-Ubiquitin-specific-processing protease 16
Supplier: Bethyl Laboratories
Supplier-Nr: A301-615A-T

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Bovine)
Immunogen: synthetic peptide. The epitope recognized by A301-615A-T maps to a region between residue 225 and 275 of human ubiquitin specific peptidase 16 using the numbering given in entry NP_006438.1 (GeneID 10600).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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