Anti-UBP51

Anti-UBP51
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES10423.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES10423.100 100 µl - -

10 - 14 business days*

290.00€
 
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,sequence... more
Product information "Anti-UBP51"
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBP-type zinc finger.,tissue specificity:Expressed in prostate, brain, lung, aorta and kidney., Protein function: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys- 16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Chromosome . Upon DNA damage, chromatin-bound USP51 disassociates from chromatin immediately following DNA damage and reassociates with chromatin following DNA repair. .
Keywords: Anti-Ubiquitin thioesterase 51, Anti-Deubiquitinating enzyme 51, Anti-Ubiquitin carboxyl-terminal hydrolase 51, Anti-Ubiquitin-specific-processing protease 51, UBP51 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES10423

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse,
Immunogen: Synthesized peptide derived from part region of human protein
MW: 78 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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