- Search results for K11366
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42 products were found matching "K11366"!
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Item number: Cay42130-1
A USP22 inhibitor, increases the levels of ubiquitinated Foxp3, a target of Usp22, in primary mouse Tregs at 10, 15, or 20 µM, reduces tumor volume and increases intratumoral levels of CD4+CD8+ T cells in an LLC1 murine lung cancer model at 20 mg/kg per day for five days. Formulation: A solid. InChI:...
| Keywords: | Ubiquitin-specific Protease 22 Inhibitor 1, Ubiquitin-specific Protease 22-IN-1, Ubiquitin-specific Protease 22i-S02,... |
| Application: | USP22 inhibitor |
| CAS | 309735-96-4 |
| MW: | 338.4 D |
From 45.00€
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Item number: ARG55541.100
Protein function: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for...
| Keywords: | Anti-USP22, Anti-KIAA1063, EC=3.4.19.12, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin... |
| Application: | IHC (paraffin), WB |
| Host: | Rabbit |
| Species reactivity: | human |
616.00€
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Item number: ARG55000.100
Protein function: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for...
| Keywords: | Anti-USP22, Anti-KIAA1063, EC=3.4.19.12, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin... |
| Application: | WB |
| Host: | Mouse |
| Species reactivity: | human |
616.00€
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Item number: ARG55003.100
Protein function: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits...
| Keywords: | Anti-Ubiquitin thioesterase 51, Anti-Deubiquitinating enzyme 51, Anti-Ubiquitin carboxyl-terminal hydrolase 51,... |
| Application: | ICC, IF, WB |
| Host: | Rabbit |
| Species reactivity: | human |
616.00€
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Item number: ATA-HPA001942.100
Protein function: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys- 16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits...
| Keywords: | Anti-Ubiquitin thioesterase 51, Anti-Deubiquitinating enzyme 51, Anti-Ubiquitin carboxyl-terminal hydrolase 51,... |
| Application: | ICC, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
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Item number: ATA-HPA044980.100
Protein function: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for...
| Keywords: | Anti-USP22, Anti-KIAA1063, EC=3.4.19.12, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
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Item number: ATA-HPA077264.100
Protein function: Deubiquitinase that can reduce the levels of BCL2L11/BIM ubiquitination and stabilize BCL2L11 in response to the RAF-MAPK- degradation signal. By acting on BCL2L11 levels, may counteract the anti-apoptotic effects of MAPK activity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2)....
| Keywords: | Anti-USP27X, Anti-USP22L, EC=3.4.19.12, Anti-Ubiquitin thioesterase 27, Anti-Deubiquitinating enzyme 27, Anti-Ubiquitin... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 369.00€
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Item number: NSJ-RQ7258
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ubiquitin specific peptidase 22 is a protein that in humans is encoded by the USP22 gene on chromosome 17. Enables enzyme binding activity, nuclear receptor coactivator activity, and thiol-dependent deubiquitinase. Contributes to H4 histone acetyltransferase...
| Keywords: | Anti-USP22, Anti-KIAA1063, EC=3.4.19.12, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
790.00€
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Item number: CSB-RA067358A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: USP22. Antigen Species: Human
| Keywords: | Anti-USP22, Anti-KIAA1063, EC=3.4.19.12, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin... |
| Application: | ELISA, IF, FC |
| Host: | Rabbit |
| Species reactivity: | human |
From 201.00€
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Item number: CSB-RA784212A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: USP22. Antigen Species: Human
| Keywords: | Anti-USP22, Anti-KIAA1063, EC=3.4.19.12, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin... |
| Application: | ELISA, WB, IHC, IF, FC |
| Host: | Rabbit |
| Species reactivity: | human |
From 201.00€
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Item number: G-AGMB02929.100
USP22 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Deubiquitinase that plays a role in several cellular processes including transcriptional regulation, cell cycle progression or innate immunity. As part of the transcription regulatory histone acetylation...
| Keywords: | Anti-USP22, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin carboxyl-terminal hydrolase... |
| Application: | WB, ICC/IF, FC, IP |
| Host: | Rabbit |
| Species reactivity: | human |
From 134.00€
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Item number: G-AGMB00084.100
USP22 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Deubiquitinase that plays a role in several cellular processes including transcriptional regulation, cell cycle progression or innate immunity. As part of the transcription regulatory histone acetylation...
| Keywords: | Anti-USP22, Anti-Ubiquitin thioesterase 22, Anti-Deubiquitinating enzyme 22, Anti-Ubiquitin carboxyl-terminal hydrolase... |
| Application: | WB, IHC-P, IP |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 134.00€
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