Anti-Tuberin Recombinant

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-RC-7035.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-RC-7035.100	100 µl		-	-	Request delivery time estimate		295.00€

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Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or... more

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Product information "Anti-Tuberin Recombinant"

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, PubMed:28215400). Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1 (PubMed:15340059). May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5. [The UniProt Consortium]

Keywords:	Anti-Tuberin, Anti-Tuberous sclerosis 2 protein, Recombinant TSC2 Antibody
Supplier:	Absea
Supplier-Nr:	RC-7035

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	3L92
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Format:	Solution

Database Information

KEGG ID :	K07207 \| Matching products
UniProt ID :	P49815 \| Matching products
Gene ID :	GeneID 7249 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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