Anti-TNIK

Item number	Size	Manual	Delivery time	Price
A302-695A-T	20 µl (2 blots)	-	3 - 9 business days*	131.00€
A302-695A-M	100 µl (10 blots)	-	3 - 9 business days*	313.00€
A302-695A	100 µl (100 µg)	-	3 - 9 business days*	465.00€

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Protein function: Serine/threonine kinase that acts as an essential activator of the Wnt... more

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Product information "Anti-TNIK"

Protein function: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322. [The UniProt Consortium]

Keywords:	Anti-TNIK, Anti-KIAA0551, EC=2.7.11.1, Anti-TRAF2 and NCK-interacting protein kinase
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-695A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Reactivity:	Human (Expected: Mouse)
Immunogen:	synthetic peptide. The epitope recognized by A302-695A-T maps to a region between residue 600 and 650 of human TRAF2 and NCK interacting kinase using the numbering given in entry NP_055843.1 (GeneID 23043).
Format:	Antigen Affinity Purified