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Product information "Anti-TIRAP (Toll-interleukin 1 receptor domain-containing adaptor protein)"
Protein function: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. [The UniProt Consortium]
Anti-Mal, Anti-Tirap, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR domain-containing adapter protein, Anti-Toll/interleukin-1 receptor domain-containing adapter protein