Anti-TDP1

Anti-TDP1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-619A-T 10 µl (10 µg) -

3 - 9 business days

125.00€
A301-619A 100 µl (100 µg) -

3 - 9 business days

443.00€
 
Protein function: DNA repair enzyme that can remove a variety of covalent adducts from DNA... more
Product information "Anti-TDP1"
Protein function: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate. [The UniProt Consortium]
Keywords: Anti-TDP1, Anti-Tyr-DNA phosphodiesterase 1, Anti-Tyrosyl-DNA phosphodiesterase 1
Supplier: Bethyl Laboratories
Supplier-Nr: A301-619A-T

Properties

Application: IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Gorilla, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-619A-T maps to a region between residue 75 and 125 of human tyrosyl-DNA phosphodiesterase 1 using the numbering given in entry NP_001008744.1 (GeneID 55775).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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