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You can also order using info@biomol.com or FAX at 0049-40-85326022
Bigger quantity required? Request Bulk
Bigger quantity required? Request Bulk
Protein function: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx... more
Product information "Anti-STIM2"
Protein function: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx. [The UniProt Consortium]
Keywords: | Anti-STIM2, Anti-KIAA1482, Anti-Stromal interaction molecule 2 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A304-430A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Reactivity: | Human, Mouse (Expected: Sheep, Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Cetartiodactyla, White-tufted-ear Marmoset, Chinese Hamster, Cat, Naked Mole Rat, Crab-eating Macaque, Chinese Tree Shrew) |
Immunogen: | synthetic peptide. The epitope recognized by A304-430A-T maps to a region between residue 650 to 700 of human Stromal Interaction Molecule 2 using the numbering given in entry NP_065911.3 (GeneID 57620). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K18196 | Find alternatives |
UniProt ID : | Q9P246 | Find alternatives |
Gene ID | GeneID 57620 | Find alternatives |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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