Anti-SPI1

Anti-SPI1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-52113.20 20 µl -

7 - 16 business days*

71.00€
E-AB-52113.60 60 µl -

7 - 16 business days*

143.00€
E-AB-52113.120 120 µl -

7 - 16 business days*

238.00€
E-AB-52113.200 200 µl -

7 - 16 business days*

396.00€
 
SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and... more
Product information "Anti-SPI1"
SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.SPI1 (Spi-1 Proto-Oncogene) is a Protein Coding gene. Diseases associated with SPI1 include Inflammatory Diarrhea and Interdigitating Dendritic Cell Sarcoma. Among its related pathways are Validated targets of C-MYC transcriptional repression and C-MYB transcription factor network. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA binding. An important paralog of this gene is SPIB. Protein function: Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA- 3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. [The UniProt Consortium]
Keywords: Anti-SPI1, Anti-Transcription factor PU.1, Anti-31 kDa-transforming protein, SPI1 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-52113

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human SPI1

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-SPI1"
Write a review
or to review a product.
Viewed