Anti-SMYD2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-011A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A303-011A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Protein-lysine N-methyltransferase that methylates both histones and... more

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Product information "Anti-SMYD2"

Protein function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. [The UniProt Consortium]

Keywords:	Anti-KMT3C, Anti-SMYD2, Anti-HSKM-B, EC=2.1.1.-, EC=2.1.1.43, Anti-Lysine N-methyltransferase 3C, Anti-Histone methyltransferase SMYD2, Anti-N-lysine methyltransferase SMYD2, Anti-SET and MYND domain-containing protein 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-011A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: chicken, bovine, pig)
Immunogen:	synthetic peptide. The epitope recognized by A303-011A-T maps to a region between residue 383 and 433 of human SET and MYND Domain Containing 2 using the numbering given in entry NP_064582.2 (GeneID 56950).
Format:	Antigen Affinity Purified