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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| 600-401-MG0S | 25 µl | - | - |
6 - 10 business days* |
180.00€
|
||
| 600-401-MG0 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This affinity purified antibody is directed against human SMO. This product was affinity... more
Product information "Anti-Smoothened"
This affinity purified antibody is directed against human SMO. This product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to mouse and rat. Protein function: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation. [The UniProt Consortium]
| Keywords: | Anti-SMO, Anti-SMOH, Anti-Protein Gx, Anti-Smoothened homolog |
| Supplier: | Rockland Immunochemicals |
| Supplier-Nr: | 600-401-MG0 |
Properties
| Application: | ELISA, IHC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | synthetic peptide corresponding to an internal portion of human Smoothened conjugated to Keyhole Limpet Hemocyanin (KLH). |
| Format: | Purified |
Database Information
| KEGG ID : | K06226 | Matching products |
| UniProt ID : | Q99835 | Matching products |
| Gene ID | GeneID 6608 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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