Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-436A-T 20 µl (2 blots) -

3 - 9 business days*

A302-436A-M 100 µl (10 blots) -

3 - 9 business days*

A302-436A 100 µl (100 µg) -

3 - 9 business days*

Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3... more
Product information "Anti-SKP2"
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration. [The UniProt Consortium]
Keywords: Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase kinase-associated protein 2, Anti-Cyclin-A/CDK2-associated protein p45
Supplier: Bethyl Laboratories
Supplier-Nr: A302-436A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-436A-T maps to a region between residue 1 and 50 of human S-phase kinase-associated protein 2 using the numbering given in entry NP_005974.2 (GeneID 6502).
Format: Antigen Affinity Purified

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Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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