Anti-SIRT6, CT (SIRT6, SIR2L6, NAD-dependent protein deacetylase sirtuin-6, Regulatory protein SIR2

Anti-SIRT6, CT (SIRT6, SIR2L6, NAD-dependent protein deacetylase sirtuin-6, Regulatory protein SIR2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
041763.200 200 µl - -

1 - 19 business days

557.00€
 
NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of... more
Product information "Anti-SIRT6, CT (SIRT6, SIR2L6, NAD-dependent protein deacetylase sirtuin-6, Regulatory protein SIR2"
NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein (By similarity). Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-SIRT6, Anti-SIR2L6, EC=3.5.1.-, Anti-SIR2-like protein 6, Anti-Regulatory protein SIR2 homolog 6, Anti-NAD-dependent protein deacetylase sirtuin-6
Supplier: United States Biological
Supplier-Nr: 041763

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: SIRT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-305 amino acids from the C-terminal region of human SIRT6.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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