Anti-SIRP alpha Recombinant Monoclonal

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A700-049-T 10 µl (5+ tests) -

3 - 9 business days*

131.00€
A700-049 100 µl (50+ tests) -

3 - 9 business days*

493.00€
 
Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and... more
Product information "Anti-SIRP alpha Recombinant Monoclonal"
Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. [The UniProt Consortium]
Keywords: Anti-BIT, Anti-Bit, Anti-p84, Anti-SIRPA, Anti-CD172a, Anti-SHPS-1, Anti-Sirp-alpha-2, Anti-Sirp-alpha-3, Anti-Sirp-alpha-1, Anti-MyD-1 antigen, Anti-SHP substrate 1, Anti-Inhibitory receptor SHPS-1, Anti-Macrophage fusion receptor
Supplier: Bethyl Laboratories
Supplier-Nr: A700-049

Properties

Application: WB, IP, IHC, ICC
Antibody Type: Monoclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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