Anti-SIRP alpha

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-EL4 100 µg - -

3 - 9 business days*

506.00€
 
Anti-SIRP alpha Antibody is purified by DEAE purification methods. Recognizes SIRP alpha 1, 2 and... more
Product information "Anti-SIRP alpha"
Anti-SIRP alpha Antibody is purified by DEAE purification methods. Recognizes SIRP alpha 1, 2 and 3. Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. [The UniProt Consortium]
Keywords: Anti-p84, Anti-BIT, Anti-Bit, Anti-SIRPA, Anti-CD172a, Anti-SHPS-1, Anti-Sirp-alpha-1, Anti-Sirp-alpha-3, Anti-Sirp-alpha-2, Anti-MyD-1 antigen, Anti-SHP substrate 1, Anti-Inhibitory receptor SHPS-1, Anti-Macrophage fusion receptor, Anti-Signal-regulatory
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-EL4

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Peptide corresponding to amino acids near the C-terminus of human SIRP alpha 1. The sequences of the immunogenic peptide differ from those of mouse, rat and bovine by one amino acid.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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