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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-EL4 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-SIRP alpha Antibody is purified by DEAE purification methods. Recognizes SIRP alpha 1, 2 and... more
Product information "Anti-SIRP alpha"
Anti-SIRP alpha Antibody is purified by DEAE purification methods. Recognizes SIRP alpha 1, 2 and 3. Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. [The UniProt Consortium]
Keywords: | Anti-p84, Anti-BIT, Anti-Bit, Anti-SIRPA, Anti-CD172a, Anti-SHPS-1, Anti-Sirp-alpha-1, Anti-Sirp-alpha-3, Anti-Sirp-alpha-2, Anti-MyD-1 antigen, Anti-SHP substrate 1, Anti-Inhibitory receptor SHPS-1, Anti-Macrophage fusion receptor, Anti-Signal-regulatory |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-EL4 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Peptide corresponding to amino acids near the C-terminus of human SIRP alpha 1. The sequences of the immunogenic peptide differ from those of mouse, rat and bovine by one amino acid. |
Format: | Purified |
Database Information
KEGG ID : | K06551 | Matching products |
UniProt ID : | P78324 | Matching products |
Gene ID | GeneID 140885 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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