Anti-SET7

Anti-SET7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-747A-T 20 µl (2 blots) -

3 - 9 business days

125.00€
A301-747A-M 100 µl (10 blots) -

3 - 9 business days

299.00€
A301-747A 100 µl (20 µg) -

3 - 9 business days

443.00€
 
Protein function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone... more
Product information "Anti-SET7"
Protein function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. [The UniProt Consortium]
Keywords: Anti-SETD7, Anti-SET7/9, Anti-KIAA1717, EC=2.1.1.43, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-SET domain-containing protein 7, Anti-Histone H3-K4 methyltransferase SETD7, Anti-Histone-lysine N-methyltransferase SETD7
Supplier: Bethyl Laboratories
Supplier-Nr: A301-747A-T

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, Chinese Hamster, Small-eared Galago, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-747A-T maps to a region between residue 316 and 366 of human SET domain containing (lysine methyltransferase) 7 using the numbering given in entry NP_085151.1 (GeneID 80854).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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