Anti-Set9

Anti-Set9
Item number Size Datasheet Manual SDS Delivery time Quantity Price
100-401-V83 100 µl - -

6 - 10 business days*

641.00€
 
Anti-Set9 Antibody is monospecific antiserum processed by delipidation and defibrination followed... more
Product information "Anti-Set9"
Anti-Set9 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Set8 from species other than human not tested. Protein function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. [The UniProt Consortium]
Keywords: Anti-SETD7, Anti-SET7/9, Anti-KIAA1717, EC=2.1.1.43, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-SET domain-containing protein 7, Anti-Histone H3-K4 methyltransferase SETD7, Anti-Histone-lysine N-methyltransferase SETD7
Supplier: Rockland Immunochemicals
Supplier-Nr: 100-401-V83

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant protein of human Set9.
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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