Anti-Sequestosome-1

Anti-Sequestosome-1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-856A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-856A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-856A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Autophagy receptor that interacts directly with both the cargo to become... more
Product information "Anti-Sequestosome-1"
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin- 1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. [The UniProt Consortium]
Keywords: Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62, Anti-EBI3-associated protein of 60 kDa, Anti-Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
Supplier: Bethyl Laboratories
Supplier-Nr: A302-856A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Rat, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A302-856A-T maps to a region between residue 375 and 425 of human Sequestosome-1 using the numbering given in entry NP_003891.1 (GeneID 8878).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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