Anti-SEMA5A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA004632.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA004632.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans,... more

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Product information "Anti-SEMA5A"

Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 91%

Keywords:	Anti-SEMAF, Anti-SEMA5A, Anti-Sema F, Anti-Semaphorin-F, Anti-Semaphorin-5A
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA004632

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PWTKCSATCG GGHYMRTRSC SNPAPAYGGD ICLGLHTEEA LCNTQPCPES WSEWSDWSEC EASGVQVRAR QCILLFPMGS QCSGNTTESR PCVFDSNFIP EVSVARSSSV EEKRCGE (ATA-APrEST85139)