Anti-S1P1

Anti-S1P1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10005228-1 1 each -

3 - 10 business days*

324.00€
 
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G-protein-coupled... more
Product information "Anti-S1P1"
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G-protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P1 primarily couples with pertussis toxin-sensitive Gi/o proteins to mediate S1P-induced cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Expression of S1P1 is abundant in embryological vasculature and is ubiquitously expressed in adult cells suggesting diverse physiological functions of this receptor. The human and mouse S1P1 receptors have 382 amino acids with an estimated molecular weight of 43 kDa. Glycosylation at the N-terminal extracellular domain may cause the protein to migrate at a higher position in SDS-PAGE. Cayman's S1P1 Polyclonal Antibody detects the receptor at 47 kDa by WB analysis. The antibody can also be used for IF and IHC to study expression patterns of this protein. Synonyms: EDG-1, S1PR1, Sphingosine-1-phosphate Receptor 1. Immunogen: Peptide from an internal cytoplasmic region of human S1P1. Formulation: 500 µl of peptide affinity-purified IgG. Storage Buffer: TBS, pH 7.4, 50% glycerol, 0.1% BSA, and 0.02% sodium azide. Host: Rabbit. Applications: IF, IHC, and WB. UniProt Accession #: P21453. Origin: Animal/Rabbit.
Keywords: Anti-S1P1, Anti-S1P1, Anti-S1PR1, Anti-CD363, Anti-CD363, Anti-CHEDG1, Anti-S1P receptor 1, Anti-S1P receptor 1, Anti-S1P receptor Edg-1, Anti-S1P receptor Edg-1, Anti-Sphingosine 1-phosphate receptor 1, Anti-Sphingosine 1-phosphate receptor 1, Anti-Sphin
Supplier: Cayman Chemical
Supplier-Nr: 10005228

Properties

Application: IF, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Immunogen: Peptide from an internal cytoplasmic region of human S1P1
Format: Solid

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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