Anti-rsks-1

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Serine/threonine-protein kinase which regulates mRNA translation (PubMed:17266680). Negatively regulates lifespan and resistance to starvation, oxidative stress, protein aggregation and P.aeruginosa-mediated infection (PubMed:17266680, PubMed:23879233, PubMed:24332851). May regulate these processes by preventing the activation of transcription factor hif-1 (PubMed:23879233). Required, probably downstream of let-363/TOR, for the establishment of the proper number of germline progenitors by promoting cell cycle progression and preventing differentiation during larval development. Regulates germ cell size (PubMed:22278922). In addition required for sperm production and embryo viability (PubMed:17266680, PubMed:22278922). Involved in axon regeneration of PLM and ALM neurons by inhibiting growth cone formation early after axotomy and later by inhibiting axon extension. Functions in axon regeneration and lifespan probably by preventing aak- 2/AMPK activation (PubMed:24332851, PubMed:24431434). Negatively regulates autophagy (PubMed:22560223). [The UniProt Consortium]