The following products have been found matching your search "K04688": 140

p70 Ribosomal S6 kinase (p70S6K) is a serine/threonine kinase that is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. LY2584702 is a selective, cell-permeable p70S6K inhibitor (IC50 = 4 nM). It blocks phosphorylation of p70S6K in primary rat hepatocytes without affecting the...

Protein function: Phosphorylates specifically ribosomal protein S6. [The UniProt Consortium]

Protein function: Downstream effector of TOR signaling pathway involved in osmotic stress response (PubMed:20683442). Could be involved in the control of plant growth and development (PubMed:20683442). Phosphorylates the ribosomal proteins P14, P16 and S6 (PubMed:20683442). Functions as a repressor of cell...

AT-13148 is an orally bioavailable and ATP-competitive multi-AGC kinase inhibitor. It inhibits Akt1, 2, and 3 (IC50s = 38, 402, and 50 nM, respectively), in addition to other AGC kinase family members p70S6K, PKA, ROCK-I, and ROCK-II (IC50s = 3-8 nM). AT-13148 inhibits growth of cancer cell lines with genetic...

ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through...

ELISA Type: Sandwich. Sensitivity: 0.094ng/mL. Range: 0.156--10ng/mL. Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through...

Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Ribosomal protein S6 kinase, 70kD, p70 S6 kinase alpha, RPS6KB1 Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and...

Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by...

Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by...

Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by...