Anti-RORgamma

Anti-RORgamma
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay11003-1 1 each -

1 - 10 business days

282.00€
 
RORgamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR... more
Product information "Anti-RORgamma"
RORgamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. RORgamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR-gamma shares 50 to 51% sequence identity with RORalpha and RORbeta and is 88% identical to mouse RORgamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.
Keywords: Anti-RORC, Anti-NR1F3, Anti-Nuclear receptor ROR-gamma, Anti-Nuclear receptor RZR-gamma, Anti-Retinoid-related orphan receptor-gamma, Anti-Nuclear receptor subfamily 1 group F member 3
Supplier: Cayman Chemical
Supplier-Nr: 11003-1

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: peptide within the region of amino acids 1-50 of human ROR-?
Format: Solid

Database Information

KEGG ID : K08534 | Search using KEGG ID
UniProt ID : P51449 | Search using UniProt ID

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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