Anti-ROC2, CT

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
100-401-A14	100 µl		-	-	6 - 10 business days*		733.00€

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Protein function: Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase... more

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Product information "Anti-ROC2, CT"

Protein function: Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents. [The UniProt Consortium]

Keywords:	Anti-RNF7, Anti-RBX2, Anti-Rbx2, Anti-CKBBP1, Anti-RING-box protein 2, Anti-RING finger protein 7, Anti-Regulator of cullins 2, Anti-CKII beta-binding protein 1, Anti-Sensitive to apoptosis gene protein
Supplier:	Rockland Immunochemicals
Supplier-Nr:	100-401-A14

Properties

Application:	ELISA, IHC, IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, zebrafish, c.elegans
Immunogen:	synthetic peptide corresponding to amino acids 102-113 of human ROC2 (C-terminal)
MW:	12.6 kD
Format:	Serum