Anti-RFWD3

Anti-RFWD3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-398A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A301-398A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A301-398A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the... more
Product information "Anti-RFWD3"
Protein function: E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair. [The UniProt Consortium]
Keywords: Anti-RFWD3, Anti-RNF201, EC=2.3.2.27, Anti-RING finger protein 201, Anti-E3 ubiquitin-protein ligase RFWD3, Anti-RING-type E3 ubiquitin transferase RFWD3, Anti-RING finger and WD repeat domain-containing protein 3
Supplier: Bethyl Laboratories
Supplier-Nr: A301-398A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Pig, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating Macaque, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-398A-T maps to a region between residue 724 and774 of human ring finger and WD repeat domain 3 using the numbering given in entry NP_060594.3 (GeneID 55159).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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