Anti-Recombinant STING, clone A369
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-AN301666L.50 | 50 µl | - |
7 - 16 business days* |
304.00€
|
|||
| E-AN301666L.100 | 100 µl | - |
7 - 16 business days* |
464.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
STING has several transmembrane domains, and is expressed in a variety of endothelial cells,... more
Product information "Anti-Recombinant STING, clone A369"
STING has several transmembrane domains, and is expressed in a variety of endothelial cells, epithelial cells and hematopoietic liver cells. STING participates in the DNA-mediated innate immune response. Non-CpG double-stranded DNA from viruses or bacteria binds to cGAS protein and is catalyzed to the second messenger cGAMP, then the dimerized STING binds to cGAMP and undergoes conformational changes. Through the autophagsome and the endoplasmic reticulum and the Golgi apparatus, it further enters the cytoplasm. During the period, it is ubiquitinated and recruited TBK1 protein, then phosphorylated, and then combined with IRF3, then IRF3 is phosphorylated and enters the nucleus to induce the expression of IFNs, etc. In conclusion, it can enhance the body's immune ability and kill bacteria, viruses and other pathogens to a greater extent.
| Keywords: | Anti-STING1, Anti-Transmembrane protein 173, Anti-Mediator of IRF3 activation, Anti-Stimulator of interferon genes protein, Anti-Endoplasmic reticulum interferon stimulator, Recombinant STING Monoclonal Antibody |
| Supplier: | Elabscience |
| Supplier-Nr: | E-AN301666L |
Properties
| Application: | WB, IHC, IF |
| Antibody Type: | Monoclonal |
| Clone: | A369 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant human STING fragment |
| MW: | 36 kD |
Database Information
| KEGG ID : | K12654 | Matching products |
| UniProt ID : | Q86WV6 | Matching products |
| Gene ID : | GeneID 340061 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H317 |
| P Phrases: | P261, P272, P280, P302+352, P333+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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